Protein Details: Glycine receptor subunit beta

Protein ID

ICDB_Pro_0550

Protein Name

Glycine receptor subunit beta

Gene Name

Glrb

Organism

Mus musculus (Mouse)

Length

496 amino acids

AlphaFoldDB

AF-P48168-F1-model_v4.pdb

Function

Sequence

MKFSLAISFFILMSLLFEDACAKEKSSKKGKGKKKQYLCPSQQSPEDLARVPPNSTSNILNRLLVSYDPRIRPNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDFRGSDALTVDPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLFPMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKEDIEYGNCTKYYKGTGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSLASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVMLNNPKRVEAEKARIAKAEQADGKGGNAAKKNTVNGTGTPVHISTLQVGETRCKKVCTSKSDLRSNDFSIVGSLPRDFELSNYDCYGKPIEVNNGLGKPQAKNKKPPPAKPVIPTAAKRIDLYARALFPFCFLFFNVIYWSIYL

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Detected in spinal cord; brain and brain stem; especially in the periolivary region; spinal nuclei; trigeminal nucleus; medulla oblongata; pons and midbrain. Detected in the inner plexiform layer of the retina (at protein level). High levels of expression in cortex; hippocampus; thalamus and cerebellum. Detected in spinal cord.